Does Serrapeptase have side effects?

Does Serrapeptase have side effects

Does Serrapeptase have side effects? People ask this question because they may want to purchase this wonderful enzyme but have concerns whether it is going to have any side effects and is it safe to take Serrapeptase.

Serrapeptase reported side effects

Serrapeptase has been used for over 30 years to  help with many common conditions, Serrapeptase side effects are few for most people, however if you start to take Serrapeptase and any of these conditions appear, stop taking it and talk to your Doctor.


  • Skin inflammation
  • Muscle aches
  • Joint pains
  • Pneumonia
  • Skin lesions
  • Abnormalities

Always talk to your Doctor before taking any supplement especially if you are taking prescription medications like blood thinners.

Serrapeptase side effects history

Serrapeptase which is also know as Serratiopeptidase is well known for over 35 years as a supplement with anti-inflammatory properties.
For this reason it is widely used to help people with painful conditions ranging from carpal tunnel syndrome, arthritis, bursitis, and other inflammatory conditions, reported Serrapeptase side effects are few.

This particular enzyme comes from the intestine of the silkworm after it was discovered that Serrapeptase could dissolve protein, I’m talking about unwanted or harmful protein for example scars or lesions.

What is Serrapeptase or Serratiopeptidase?

It is an enzyme found in the stomach of newly born silkworm called Bombtx mori, this enzyme helps the silkworm to dissolve the cocoon surrounding it and escape.

Published research will classify Serrapeptase as a proteolytic enzyme,meaning that it can break down protein into amino acids which are basically building blocks.

Scientists discovered this and were able to isolate Serrapeptase, many studies have followed showing the value and range of the enzymes therapeutic usefulness on humans.

Clinical study Serrapeptase does Serrapeptase have since effects

Serrapeptase side effects- Published Studies

Whilst Serrapeptase is well known as an anti-inflammatory, the data supporting this goes back more than 30 years.

There was a study done a long time ago in 1984 by Pharmatherapeutica the study participants included 174 people that were tested using a procedure called Caldwell-Luc antrostomy to help with chronic empyema, these 174 people were given the supplement Serrapeptase.

Results from the study pointed to the fact that Serrapeptase could be beneficial as an anti inflammatory, analgesic and antiedemic remedy however they did point out that many more larger studies need to be done in this area.

During the study patients were asked does Serrapeptase have side effects, there were no reported Serrapeptase side effects.

A study on Serrapeptase and Chronic emphysema

Chronic emphysema is a disease that affects the maxillary sinus which is just underneath the skull, this leads to nasal discharge,obstruction and pain. Of the 172 people that took part in this clinical trial, 88 were given 10 mg of Serrapeptase up to 3 times the day before their operation.

After the operation they were given Serrapeptase 3 times daily, 1 at night for the next 5 days, the remaining eighty six people were given a placebo.

After the trial researchers found a change in the swelling of the cheek area,the 88 people who took Serrapeptase had much less swelling when compared to the remaining 86 people. The study asked the participants does Serrapeptase have side effects, the answers confirmed the absence of Serrapeptase side effects

It was established that Serrapeptase can manage inflammation, furthermore in more recent studies it has proved effective in the following conditions.

Chronic Obstructive Pulmonary Disease (COPD)

People with COPD taking Serrapeptase have been observed and reported improvements with their breathing
In a published study in Respirology, people taking Serrapeptase for 4 weeks were reported to have reduced frequency of coughing, less sputum weight, less viscosity and elasticity in the morning.

Blood Clots

The evidence suggests that Serrapeptase can dissolve damaged or dead tissue without causing any harm to healthy tissue, it can break down fibrin which is insoluble and a major part of blood clots.

Experts claim that Serrapeptase can reduce the build up of plaque in the arteries without Serrapeptase side effects, however we need more studies in this area.

Dementia/Alzheimer’s Disease

During a trial on rats Serrapeptase was shown to decrease acetylcholinesterase activity, slowing down the interleukin-6 that is found in people with Alzheimer’s/Dementia in large amounts.

This study concluded that taking Serrapeptase may have a role to play in changing some factors which characterize Alzheimer’s/ Dementia.

Swollen breasts

Swollen breasts or breast engorgement happens when a mother’s breasts are full with milk making them swollen and hard. Researchers wanted to test to find out if Serrapeptase could help.

The Singapore Medical Journal published a study in 1989 where scientists gathered a group of seventy mothers affected by breast swelling/engorgement.

Half of the mothers who received Serrapeptase reported less swelling and less pain when compared to the other 35 placebo receiving mothers..

Carpal tunnel image

Carpal tunnel syndrome (CTS)

Described as a medical condition because of compression of a median nerve when it travels through the wrist in the area of the carpal tunnel.

Symptoms are numbness,pain,tingling in the index finger and thumb, Carpal tunnel syndrome is a medical condition caused by compression to the median nerve.

In one particular study 10 mg of Serrapeptase were given to a small group of people affected by Carpal Tunnel Syndrome twice times daily for 6 weeks.

The results showed some clinical improvement in 65% of cases but carpel tunnel did come back in some cases.

Obviously, a lot more experiments need to be done in this area before we can categorically say Serrapeptase can help with Carpal Tunnel syndrome.

I hope that you have enjoyed reading my post on does Serrapeptase have side effects, according to the studies it does seem to be a good natural alternative for carpal tunnel, breast engorgement, blood clots, inflammatory conditions like bursitis, arthritis and COPD.