Nattokinase benefits and side effects

Nattokinase benefits and side effects

Have you heard about Nattokinase benefits and side effects? Let me tell you about the health benefits of Nattokinase of which there are many, it’s made from natto a Japanese food so side effects are few.

Natto benefits and side effects

What is Nattokinase?

Nattokinase is an enzyme that digests protein, Nattokinase is a particularly good enzyme because it speeds up chemical reactions in the body, it comes from a food source (natto) and has become popular as a treatment for a number of diseases associated with the circulatory system and the heart.

Nattokinase works best at reducing clotting it is helpful for cardiovascular disease symptoms, peripheral artery disease and deep vein thrombosis. The enzyme also works well at reducing swelling caused by inflammation so it is helpful to relieve joint swelling and pain.

I have written this article on Nattokinase benefits and side effects based on scientific articles that are listed at the bottom I believe that you should take scientific evidence into account before you try a new enzyme therapy, in addition there are many Nattokinase testimonials that may be helpful in helping you decide if this pretolytic enzyme is right for you.

For example here is a sample testimonial from a satisfied Nattokinase user

“I have a fib and need blood thinners. I have used this product for many years in place of the many dangerous blood thinners prescribed by doctors.

I must say that my doctor almost fires me because of my refusal to comply with his recommendations. I am doing great with the use of Nattokinase, I would also say please research carefully before you use this or any other product if you have a health condition that otherwise prescribes medication.

What a difference 1-year can make”

How is Nattokinase made?

Nattokinase comes from natto a boiled soybean popular in Japan, during a fermentation process using a bacterium Bacillus natto Nattokinase is made for consumption as a dietary supplement.

Nattokinase benefits and side effects

When was Nattokinase first discovered?

The fibrinolytic properties of Nattokinase were initially discovered quite accidentally by a researcher at Chicago university Doctor Hiroyuki Sumi was doing research on fibrin and natto accidentally fell onto a petri dish containing fibrin. He was amazed to find that the natto had completely dissolved the fibrin in no time at all, from this discovery further research has proven that Nattokinase not only helps with blood clotting but it could also be effective for high blood pressure, deep vein thrombosis, poor circulation and high cholesterol.

What is Nattokinase good for?

Let’s look at Nattokinase benefits and side effects, the enzyme is by and large safe to take, after all its main component is a popular Japanese food natto, what’s really interesting is the fact that heart disease is far lower in Japan than in the western world, could that have something to do with the consumption of natto?

We know that Nattokinase is safe to take in supplement form in doses not more than 2,000 fu per day, Nattokinase health benefits can help with

  • Heart disease
  • Poor circulation
  • Peripheral artery disease
  • High blood pressure
  • Stoke prevention
  • Clogged arteries
  • Deep vein thrombosis

Here’s how Nattokinase works for

High blood pressure

High blood pressure can be caused by narrowing of the arteries, Nattokinase can help in reducing high blood pressure by impeding the enzyme (angiotensin-converting) that is associated with narrowing of the arteries. Studies on the effects of Nattokinase on patients with high blood pressure have shown that by taking Nattokinase for up to two months can cause a noticeable difference in blood pressure.

Improves circulation

Blood clots are a common cause of poor circulation, a number of studies have shown that Nattokinase supplements decrease blood clots and reduce new blood clots forming in the legs.

Think of it as a natural blood thinner much like aspirin or warfarin without the side effects, not only that one study showed a remarkable improvement in blood flow after only five hours of taking the enzyme.

Deep vein thrombosis

Deep vein thrombosis occurs when a blood clot forms in a vein usually in the leg, this could be caused by an injury to the vein, certain medications, limited mobility, a trauma or long periods of inactivity. The Nattokinase supplement have been shown reduce blood clots in the legs, reduce pain and improve circulation.

High cholesterol

High cholesterol

During a trial of Nattokinase and high cholesterol trial participants it was found that a regular Nattokinase dosage in conjunction with a healthy diet reduced cholesterol and triglyceride amounts significantly.

Hardening of the arteries

Possibly one of the best Nattokinase benefits is its ability to reduce hardening of the arteries without side effects, hardening of the arteries is associated with atherosclerosis that can cause a heart attack, Nattokinase helps to dissolve plaque reduce cholesterol improve heart function and increase blood flow.

Alzheimer’s disease

More studies are needed however some studies show that Nattokinase may be helpful in degrading amyloid fibrils thought to be responsible in part for Alzheimer’s disease.

Poor circulation

The arteries and blood vessels are responsible for transporting oxygen rich blood and nutrients throughout the body.

If blood flow to any part of the body is reduced there will be symptoms of poor circulation mostly in the arms and kegs.

Poor circulation isn’t by itself a health condition rather a symptom of other health conditions like heart conditions, diabetes or obesity.

Nattokinase is ideal for poor circulation because it helps with heart conditions by improving blood flow to all areas of the body thus improving circulation.

Now that I have started to write this post about Nattokinase benefits and side effects the question is does Nattokinase have side effects?

Nattokinase side effects

We must keep in mind that this enzyme is a blood thinner so if you are prone to a bleeding disorder Nattokinase should be avoided because Nattokinase can thin the blood and cause complications for you.

If you are taking Nattokinase and you have major surgery scheduled you should stop up to two weeks beforehand in case of a bleed during surgery, it’s safe to resume taking it two weeks following surgery.

Nattokinase side effects are few it is a food derived (natto) supplement, I have taken Nattokinase with heart medications for more than 12 months, to be honest I have no side effects to report to you.

Blood pressure medications

Anti hypertensive drugs

This type of drug is designed to lower blood pressure the most common types are calcium channel blockers, ace inhibitors, beta blockers, angiotensin II receptor antagonists, or thiazide blockers.

If you are taking any of these prescribed drugs and if you have cardiovascular disease the chances are that you have some of these drugs in your home.

Speak to your doctor because Nattokinase can lower blood pressure so you don’t want it to go too low on case of problems.

Having said that I take Nattokinase with beta blockers for over a year now no difficulties with low blood pressure.

Anti coagulant drugs

Anti coagulant drugs are there to speed up the time it takes for the blood to clot, more commonly known as blood thinners, one that comes to mind is heparin, Nattokinase is also a blood thinner so the two may not mix well, better to consult your doctor on this one.


What is the appropriate dose for you will depend on how chronic your health condition is, how your metabolism is, how your overall health is, what medication you take, all the studies on Nattokinase show that doses of 2,000 FU up to 3 times a day were used without any side effects.

Unit of measurement

A Nattokinase supplement is measured a little differently from other supplements, if you look at the picture you will notice 2,000 FU, what does FU stand for? It means fibrinolytic units or the number of units it activates, basically the higher FU means more enzyme units in the product.

Nattokinase benefits

If you are searching for a supplement that has the ability to dissolve or break down materials in protein in plaque build-up in the arteries that are difficult to remove then why not give Nattokinase a try, not only will it help with plaque it will also keep your cholesterol down and reduce the side effects of statin drugs.

Nattokinase benefits and side effects must be measured equally to determine if the enzyme is the right one for your health.

Nattokinase and Serrapeptase

Both of these amazing enzymes are systemic meaning they work inside the body, across the world systemic enzymes are being used to help in keeping the body healthy, our bodies have their own enzymes that set off millions of chemical reactions. Chemical reactions lead to growth in the cells, cell repair, aid digestion and reproduction in the system.

Nattokinase and Serrapeptase are two of the most important enzymes that we can take however they are not the same and I will tell you why:

Both enzymes are more than helpful in supporting a healthy immune system and lowering inflammation in the body, if you are trying to make your mind up which enzyme is best for you, here is the difference.

Nattokinase and SerrapeptaseSerrapeptase

Serrapeptase can digest protein but it is also great at reducing and preventing fluid retention, Serrapeptase is used by natural health practitioners and some doctors as an anti-inflammatory treatment for their clients as an alternative to NSAIDs that don’t always suit everyone.

In a nutshell Serrapeptase is useful for conditions like:

  • Chronic inflammation
  • Gastrointestinal issues
  • Joint pain
  • Carpal tunnel syndrome
  • Blocked fallopian tubes
  • COPD
  • Ear, nose and throat conditions


When you think about Nattokinase think about the circulatory system, and what are the issues, heart disease for example is caused by plaque hardening in the arteries making the job of pumping and circulating blood and nutrients difficult for the heart.

This pressure can lead to sometime fatal consequences to compound the problem inflammation can be equally damaging as plaque build-up some experts say that inflammation is the main cause of heart attack or stroke.

Fortunately, Nattokinase is the ideal enzyme to deal with all of these issues, Nattokinase benefits include the ability to ward off plaque including calcium, cholesterol and debris in the blood, this action reduces inflammation in the arteries allowing healing of the damaged tissue to begin.

Nattokinase should be used for conditions that are affected by poor circulation or blockages in the cardiovascular system like;

  • Clogged arteries
  • Deep vein thrombosis
  • High cholesterol
  • Poor circulation
  • High blood pressure
  • Alzheimer’s

Our bodies have natural enzymes already there, how strong they are has a direct effect our body’s ability to ward off diseases, repair cell damage and keep our bodies bodies healthy. Unfortunately we can’t stay young forever so our immune system becomes depleted of some vital enzymes, a shortage of the natural enzymes can cause health issues and allow bad bacteria to go through our bodies unchecked.

When you throw in a poor diet, environmental changes, stress and a lack of enough exercise the health problems are compounded.


I sincerely hope that you have all the information on Nattokinase benefits and side effects that you need, Nattokinase is a natural solution for any number of ailments, Nattokinase is made from a food (natto) and offers many health benefits without any real side effects.

It’s main strength is the ability to dissolve harmful proteins that are blocking up the cardiovascular system it also gets rid of those harmful and toxins from the body,


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