What does Serrapeptase work for?

Written by Fintan Duggan QQI L5 Healthcare

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Serrapeptase silkworm

What does Serrapeptase work for?

Serrapeptase the enzyme is produced by isolating the bacteria in the humble silkworm, has been used throughout the world for a long time as a natural anti-inflammatory and pain reliever after surgery or a trauma, health professionals have found success using Serrapeptase for several common health conditions.

It has been put to good use for more than 30 years in Japan, Europe and the USA with a range of alleged health benefits. Discover how Serrapeptase can help you or your family in a natural way with many conditions caused by inflammation by reading this article on what does Serrapeptase work for?

What is Serrapeptase exactly?

It is known also as Serratipeptidase, it is a proteolytic enzyme that means it can break down proteins into much smaller parts called amino acids, there are other proteolytic enzymes for example bromelain, nattokinase, chymotrypsin and trypsin, these have been used mostly in the USA since the 1950’s after their anti-inflammatory properties were noticed by scientists in Japan.

Health benefits sign

Researchers in Europe and Japan were convinced that proteolytic enzymes were a real effective alternative in reducing inflammation. Since then Serrapeptase has been found to have many more beneficial health benefits for:

  • Carpal tunnel
  • Swollen knee
  • Hip Bursitis
  • Shoulder bursitis
  • Fibromyalgia
  • Blood clots
  • Swelling
  • Arthritis

Main benefits of Serrapeptase

Serrapeptase is a proteolytic enzyme meaning it can break down or dissolve blood clots, fibrin or plaque, amazingly Serrapeptase has shown in a small amount of studies to be able to do this without causing any harm in the arteries. Atherosclerosis or hardening of the arteries has a major impact on your risk of heart disease, by breaking down the plaque build-up will have the effect of reducing the risk of a heart attack or stroke.

If Serrapeptase can dissolve blood clots it must also be able to dissolve scars, fluid build-up, mucus build up and cysts, this makes Serrapeptase an attractive alternative for damaged skin following an operation or accident, sinus headache, carpal tunnel syndrome, swelling of any kind and any form of lung disease.

Serrapeptase is particularly good at helping with inflammation swelling and pain, in one study it was called “the super enzyme” with a huge list of health benefits including being just as effective as diclofenac gel used for inflammation.


NSAID’s for Inflammation

NSAID’s are commonly used to treat inflammation, prostaglandins are made in the cells of the body by an enzyme COX (cyclooxygenase) there are two of these COX 1 & COX 2, both produce prostaglandins causing inflammation in the body which can manifest itself in many conditions such as:

  • arthritis
  • bursitis
  • asthma
  • sinusitis
  • crohn’s disease
  • periodontitis
  • colitis
  • rheumatoid arthritis
  • chronic peptic ulcer

Nsaid’s are the common medicine prescribed by doctors worldwide, NSAID’s drugs block the COX enzyme helping to reduce the prostaglandins in the body thus reducing the inflammation and pain. However, it is well documented that NSAID’s have side effects for example they may cause stomach ulcers and bleeding.

Other side effects reported high blood pressure, kidney failure, osteoporosis and myopathy.

Dietary supplements

Dietary supplements for inflammation

Many dietary supplements have been touted as having natural anti-inflammatory properties, supplements like Serrapeptase, Turmeric and Devil’s Claw.

Even though there are limited clinical trials to look at many people across the world use supplements every day for the natural relief of pain and inflammation.

Even though the evidence is anecdotal it doesn’t mean that Serrapeptase should not be used for inflammation and pain, in Canada it has been passed as a ” natural product” meaning it is safe to use, keep reading what does Serrapeptase work for?

According to one Serrapeptase study it and Serratipeptidase ( a similar enzyme) could indirectly help with inflammation resolution , it has also been associated with the inhibition of pain inducing amines known as bradykinin, it is thought that Serrapeptase can be equally as effective as aspirin without the long term side effects.

What are Serrapeptase benefits

What else does it work for?

Serrapeptase is useful for other painful conditions including osteoarthritis, rheumatoid arthritis, back pain, sinusitis, fibromyalgia, migraine, carpal tunnel syndrome.

Also, very useful for pain and swelling conditions like laryngitis, sinus pressure and headache, ear infections, post-surgery scarring, blood clots, crohn’s disease and fibromyalgia.

Women with fibrocystic breast disease have reported finding relief from the symptoms, nursing mothers have reported improvements in breast engorgement (too much milk) after taking Serrapeptase.

It may also be used for atherosclerosis but the evidence that it works to remove plaque build-up in the arteries are thin on the ground. Nattokinase is a better and more effective option for reducing plaque build-up, there are some studies to show that it works well for reducing blood pressure.

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Serrapeptase Dosage

When taking Serrapeptase please make sure that you are buying the enteric coated version because any other version may dissolve in your stomach (acid) before it reaches the intestines where it will be absorbed.

In Serrapeptase studies typically the doses ranged from 1o mg – 60 mg daily, enzymatic activity is measured in units, 10 mg is equal to 20,000 units of enzymatic activity.

For severe swelling and pain start on 2 x 250,000 IU Serrapeptase per day, take it on an empty stomach one hour before a meal, similarly leave one hour after taking it before you eat. After the first 2 weeks you notice a reduction in pain, stay on the 2 tablets per day until the pain has gone altogether. On the other hand if the pain doesn’t subside increase the dosage ( I have taken 3 per day max for hip bursitis) it worked. You may have to judge for yourself how many, to be safe increase the dosage gradually.

It is recommended to stay on a maintenance dose of one a day after that.

Serrapeptase side effects

Just like any other supplement or medication each person is unique so the side effects will vary from person to person, some may not have any side effects while others will report the opposite, these are the reported side effects:

  • Upset stomach
  • Cramps
  • Nausea
  • Skin reaction

If you need any advice on Serrapeptase please contact me using the contact form.


Serrapeptase science



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