Coenzyme Q10 Benefits Statin Drugs

Cholesterol

Coenzyme Q10 Benefits Statin

The 2018 review on the legacy effects of statin drugs on cardiovascular disease and improvements in mortality rates suggested that there are many mechanisms where statin drugs may in fact increase heart disease and the risk of heart failure. One important mechanism that is affected by statin drugs is the production of Coenzyme Q10, if you wondered where you get energy from Coenzyme Q10 is responsible for energy production in our bodies. So what are Coenzyme Q10 Benefits Statin?

Coenzyme Q10 Benefits

Coenzyme Q10 is produced naturally by our bodies, it is a natural antioxidant it links with Vitamins B & C and selenium to prevent damage being done to our bodies by free radicals. Coenzyme Q10 is an enzyme and it converts carbohydrates into energy.


Study evidence

The authors of the study put forward the argument that existing and trustworthy evidence doesn’t show that by giving statin drugs to lower cholesterol doesn’t necessarily decrease the risk of heart disease. There is a worldwide acceptance that based on older studies statins reduce heart disease theses dtudies to as far back as the 1990’s. More recent clinical trials have failed time and time again to prove that statins significantly lower the risk of coronary heart disease despite the fact that they are good at lowering bad cholesterol LDL levels.

Statins may increase heart disease

How do statins increase heart disease? Through different mechanisms, for example statins inhibit biosynthetic cholesterol pathways, they suppress the synthesis of Coenzyme Q10 the enzyme that is so important to our bodies, not only that statins inhibit a haemoglobin protein Hame A vital for carrying oxygen to body tissue. Both Hame A and Coenzyme Q10 are critical parts of the electron transport chain. The result of this impairment is a reduction in ATP production and a consequent loss of energy in the body.


Long term use of Statins

Side effects from the long term use of statins include muscle pain, joint pain, stomach pain, dizziness and loss of appetite, this might explain abnormalities in structures that produce energy. Statins inhibit the production of K2, this has an effect on the prevention of blood vessel calcification, clinical trials have shown faster calcification in the coronary arteries in diabetic people who use statins at a high frequency.

Statins are known to reduce the production of selenium proteins, these work to reduce peroxidative stress, cardiomyopathy is caused by elevated levels of stress, it is thought that long term use of statins are responsible for this.

Statins and heart failure

Did you know that one of the side effects of statins is muscle weakness? The heart is a muscle so it could be affected by statin use, two studies of statin use discovered that that blood pressure was affected leading to congestive heart failure. Those same trial participants were given Coenzyme Q 10 and discontinued statins the results showed improvement in heart muscle function.


Summary

To summarize, statins may increase the risk of heart disease by increasing calcification in the arteries, statins will suppress the production of Coenzyme Q10 and Hame A making your body lose energy. Side effects of statins are common like joint and muscle pain, stomach pain, diarrhoea and loss if appetite.

Anybody who is taking prescription statin drugs and feeling less energy needs to start taking a quality Coenzyme Q10 supplement to help your body produce more energy and to offset the side effects of statin drugs.


.References:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173243/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047411/

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31942-1/fulltext


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